19 Results for "

Psoralea corylifolia L.

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Psoralea corylifolia L." in MCE Product Catalog:

15
Neobavaisoflavone
Neobavaisoflavone
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15 Publications Verification
Cat. No.: HY-N0720
CAS No.: 41060-15-5
Category:  

Flavonoids Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Cancer Isoflavones

Target:  

Apoptosis DNA/RNA Synthesis

Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation .
13
Bavachin
Bavachin
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13 Cited Publications
Cat. No.: HY-N0233
CAS No.: 19879-32-4
Synonyms: Corylifolin
Category:  

Flavonoids Leguminosae Flavonones Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Cancer

Target:  

Estrogen Receptor/ERR

Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
10
Isobavachalcone
Isobavachalcone
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10 Cited Publications
Cat. No.: HY-13065
CAS No.: 20784-50-3
Pureté:  99.01%
Synonyms: Corylifolinin; Isobacachalcone
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
6
Isobavachin
Isobavachin
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6 Cited Publications
Cat. No.: HY-N0762
CAS No.: 31524-62-6
Category:  

Flavonoids Neurological Disease Leguminosae Flavonones Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields

Target:  

Cytochrome P450 UGT p38 MAPK NF-κB NO Synthase COX Fc Receptor (FcR) RANKL/RANK Keap1-Nrf2 Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachin is an orally active, blood-brain barrier-penetrating prenylated flavonoid present in Psoralea corylifolia. Isobavachin inhibits human CYP2B6, CYP2C9, CYP2C19, UGT1A1, UGT1A9, and UGT2B7. Isobavachin suppresses MAPK activation, NF-κB nuclear translocation, overexpression of iNOS/COX-2, FcεRI-mediated signaling pathways, and RANKL-induced osteoclastogenesis. Isobavachin induces autophagy, cytotoxicity, neuronal differentiation, and NRF2 activation; it alleviates oxidative damage, inflammatory responses, apoptosis, iron accumulation, mitochondrial biogenesis, and mast cell degranulation. Isobavachin is applicable to research related to liver injury, inflammatory diseases, osteoporosis, liver cancer, prostate cancer, glioma, periodontitis-induced bone loss, and Alzheimer's disease .
12-Hydroxyisobakuchiol
12-Hydroxyisobakuchiol
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Cat. No.: HY-N10895
CAS No.: 178765-55-4
Category:  

Monophenols Leguminosae Phenols Psoralea corylifolia L. Plants

Target:  

Fungal

12-Hydroxyisobakuchiol is a hemiterpenoid compound that can be isolated from the leaves of Psoralea glandulosa. 12-Hydroxyisobakuchiol inhibits mycelial growth of Botrytis cinerea in vitro. 12-Hydroxyisobakuchiol is applicable to research related to phytopathogenic fungal infections .
13-Hydroxyisobakuchiol
13-Hydroxyisobakuchiol
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Cat. No.: HY-N7506
CAS No.: 178765-49-6
Synonyms: Delta3,2-Hydroxylbakuchiol
Category:  

Monophenols Leguminosae Phenols Psoralea corylifolia L. Plants

Target:  

Monoamine Transporter Dopamine Transporter

13-Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol (HY-N0235) that can be isolated from Psoralea corylifolia (L.), is a potent selective monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50 = 0.58 μM) and norepinephrine transporter (NET) (IC50 = 0.69 μM) than for the serotonin transporter (SERT) (IC50 = 312.02 μM). 13-Hydroxyisobakuchiol increases the activity of intact mice and improves the decreased activity of reserpinized mice in vivo. 13-Hydroxyisobakuchiol can be used for the research of disorders such as Parkinson's disease and depression .
Psoralenoside
Psoralenoside
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Cat. No.: HY-N7503
CAS No.: 905954-17-8
Category:  

Infection Leguminosae Simple Phenylpropanols Metabolic Disease Psoralea corylifolia L. Phenylpropanoids Plants Disease Research Fields

Target:  

Drug Intermediate Bacterial

Psoralenoside is an orally active benzofuran glycoside. Psoralenoside is isolated from the fruits of Psoralea corylifolia. As a metabolite precursor, Psoralenoside undergoes deglycosylation by intestinal flora to form Psoralen (HY-N0053). Psoralenoside is applicable to research related to cancer and bacterial infections .
Isopsoralenoside
Isopsoralenoside
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Cat. No.: HY-N7504
CAS No.: 905954-18-9
Category:  

Infection Leguminosae Ketones, Aldehydes, Acids Metabolic Disease Psoralea corylifolia L. Plants Disease Research Fields

Target:  

Bacterial

Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .
Furano(2'',3'',7,6)-4'-hydroxyflavanone
Furano(2'',3'',7,6)-4'-hydroxyflavanone
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Cat. No.: HY-N9184
CAS No.: 1454619-70-5
Category:  

Flavonoids Leguminosae Flavonones Psoralea corylifolia L. Plants

Target:  

Others

Furano(2'',3'',7,6)-4'-hydroxyflavanone is a Flavonoids product that can be isolated from the seeds of Psoralea corylifolia. .
Psoracorylifol C
Psoracorylifol C
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Cat. No.: HY-N10820
CAS No.: 879290-99-0
Category:  

Microorganisms Leguminosae Coumarins Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Bacterial

Psoracorylifol C is a natural product. Psoracorylifol C has important activity against Helicobacter pylori. Psoracorylifol C can be isolated from the seeds of Psoralea corylifolia .
Neobavaisoflavone (Standard)
Neobavaisoflavone (Standard)
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Cat. No.: HY-N0720R
CAS No.: 41060-15-5
Category:  

Flavonoids Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Isoflavones

Target:  

Reference Standards Apoptosis DNA/RNA Synthesis

Neobavaisoflavone (Standard) is the analytical standard of Neobavaisoflavone. This product is intended for research and analytical applications. Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation .
Psoralenoside (Standard)
Psoralenoside (Standard)
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Cat. No.: HY-N7503R
CAS No.: 905954-17-8
Category:  

Leguminosae Simple Phenylpropanols Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Reference Standards Histamine Receptor Calcium Channel Calmodulin

Psoralenoside is a benzofuran glycoside from Psoralea corylifolia . Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol) . Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .
Bavachromene
Bavachromene
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Cat. No.: HY-121236
CAS No.: 41743-38-8
Category:  

Flavonoids Chalcones Leguminosae Other Diseases Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields

Target:  

Others

Bavachromene is a chromenochalcone from the seeds of Psoralea corylifolia with estrogenic activities .
Bakuchicin
Bakuchicin
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Cat. No.: HY-N11698
CAS No.: 4412-93-5
Synonyms: Allopsoralen
Category:  

Leguminosae Coumarins Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Topoisomerase

Bakuchicin (Allopsoralen) is a compound that can be found in Psoralea corylifolia. It has certain inhibitory activity against topoisomerase II. In the cell model infected with Simian virus 40 (SV40), the IC50 of Bakuchicin against topoisomerase II is 404 μM. Bakuchicin can be used in the research of the anti-infection field .
Isobavachalcone (Standard)
Isobavachalcone (Standard)
0 Images
Cat. No.: HY-13065R
CAS No.: 20784-50-3
Synonyms: Corylifolinin (Standard); Isobacachalcone (Standard)
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Glycyrrhiza uralensis Fisch.

Target:  

Reference Standards Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Standard) is the analytical standard of Isobavachalcone. This product is intended for research and analytical applications. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
Bavachin (Standard)
Bavachin (Standard)
0 Images
Cat. No.: HY-N0233R
CAS No.: 19879-32-4
Synonyms: Corylifolin (Standard)
Category:  

Flavonoids Leguminosae Flavonones Phenols Polyphenols Psoralea corylifolia L. Plants

Target:  

Reference Standards Estrogen Receptor/ERR

Bavachin (Standard) is the analytical standard of Bavachin. This product is intended for research and analytical applications. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
Isoficusin A
Isoficusin A
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Cat. No.: HY-N9242
CAS No.: 1914963-20-4
Category:  

Flavonoids Leguminosae Psoralea corylifolia L. Plants Fabaceae

Target:  

Others

Isoficusin A is a Flavonoids product that can be isolated from the seeds of Psoralea corylifolia Linn. .
8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen
8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen
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Cat. No.: HY-N9288
CAS No.: 151121-39-0
Category:  

Leguminosae Coumarins Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Others

8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen is a Coumarins product that can be isolated from the herbs of Psoralea corylifolia L. .
Licoagrocarpin
Licoagrocarpin
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Cat. No.: HY-186188
CAS No.: 202815-29-0
Category:  

Glycyrrhiza glabra Linn. Flavonoids Leguminosae Plants Other Flavonoids

Target:  

Drug Intermediate

Licoagrocarpin is an isoprenylated pterocarpan, a type of naturally occurring flavonoid found in the roots of Glycyrrhiza glabra. Licoagrocarpin serves as a precursor in the biosynthetic pathway of Glabridin (HY-N0393) .
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Assay Types